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Table of Contents
Brain Information Flow Diagram (BIF)
WBAI proposes the Brain Information Flow Diagram (BIF) as a format for describing and sharing the whole brain architecture (cf. information flow diagram).
Overview
BIF is composed of Circuits and Connections between them. A Circuit corresponds to a population of neurons, an organ in the brain such as the hippocampus, or a circuit consisting of brain organs, to perform a certain function.
The BIF Ontology
BIF elements are defined by an ontology with the following classes and properties. Circuits and Connections are normally defined as classes rather than instances.
Circuit
A collection of one or more brain regions or organs with the following properties.
- names: name list
- hasPart: Circuits within
- functionality: description of functions
- reference: reference list
- implementation: URLs (pointers to implementation)
- uniform: truth value (true iff it has no sub-Circuit and unique output)
- taxon : animal species (option)
UniformCircuit
A subclass of Circuit whose instance has unique output and no sub-Circuit
- uniform: True
They have the following properties in addition to the properties of Circuit.
- size: natural number (such as the number of neurons)
- transmitter: neurotransmitter
- modType: Excitatory, Inhibitory, Modulatory
Connection
Connections between Circuits with the following properties.
NeuroTransmitter
Neurotransmitter: e.g., dopamine
Preparing BIF data
Please refer to the BIF data preparation manual.