This is an old revision of the document!

Brain Information Flow Diagram (BIF)

WBAI proposes the Brain Information Flow Diagram (BIF) as a format for describing and sharing the whole brain architecture (cf. information flow diagram).

BIF is composed of Circuits and Connections between them. A Circuit corresponds to a population of neurons, an organ in the brain such as the hippocampus, or a circuit consisting of brain organs, to perform a certain function.

BIF elements are defined by an ontology with the following classes and properties.
Circuits and Connections are normally defined as classes rather than instances.


A collection of one or more brain regions or organs with the following properties.

  • names: name list
  • hasPart: Circuits within
  • functionality: description of functions
  • reference: reference list
  • implementation: URLs (pointers to implementation)
  • uniform: truth value (true iff it has no sub-Circuit and unique output)
  • taxon : animal species (option)


A subclass of Circuit whose instance has unique output and no sub-Circuit

  • uniform: True

They have the following properties in addition to the properties of Circuit.

  • size: natural number (such as the number of neurons)
  • transmitter: neurotransmitter
  • modType: Excitatory, Inhibitory, Modulatory


Connections between Circuits with the following properties.

  • inputCircuit: a Circuit
  • outputCircuit: a Circuit
  • transmitter: neurotransmitter
  • functionality: description of function/semantics
  • reference: reference list
  • size: natural number (such as the number of axons)
  • taxon: animal species


Neurotransmitter: e.g., dopamine

  • brain_information_flow.1591356596.txt.gz
  • Last modified: 2020/06/05 20:29
  • by n.arakawa